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Postoperative wounds are those wounds acquired during surgical procedures. Postoperative wound healing occurs after surgery and normally follows distinct bodily reactions: the inflammatory response, the proliferation of cells and tissues that initiate healing, and the final remodeling.
The wound-healing process is not only complex but fragile, and it is susceptible to interruption or failure leading to the formation of non-healing chronic wounds. Factors that contribute to non-healing chronic wounds are diabetes , venous or arterial disease , infection, and metabolic deficiencies of old age.
Delayed tissue injury with impaired wound healing capability often develops after receiving doses in excess of 65 Gy. A diffuse injury pattern due to the external beam radiotherapy's holographic isodosing occurs. While the targeted tumor receives the majority of radiation, healthy tissue at incremental distances from the center of the tumor are ...
The extent of the injury and the age of the injured person may contribute to the likelihood of complications. Infection of wounds is a common complication in traumatic injury, resulting in diagnoses such as pneumonia or sepsis. [63] Wound infection prevents the healing process from taking place and can cause further damage to the body.
The embryo and fetus are considered highly sensitive to radiation exposure. [8] Complications from radiation exposure include malformation of internal organs, reduction of IQ, and cancer formation. [8] The SI unit of exposure is the coulomb per kilogram (C/kg), which has largely replaced the roentgen (R). [9]
Studies have been performed on the use of shortwave radiation for cancer therapy and promoting wound healing, with some success. However, at a sufficiently high energy level, shortwave energy can be harmful to human health, potentially causing damage to biological tissues, for example by overheating or inducing electrical currents. [28]
Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. [1] Symptoms can start within an hour of exposure, and can last for several months.
Radiation dermatitis (also known as radiodermatitis) is a skin disease associated with prolonged exposure to ionizing radiation. [ 3 ] : 131–2 Radiation dermatitis occurs to some degree in most patients receiving radiation therapy, with or without chemotherapy.