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  2. Cytosine - Wikipedia

    en.wikipedia.org/wiki/Cytosine

    Cytosine (/ ˈ s aɪ t ə ˌ s iː n,-ˌ z iː n,-ˌ s ɪ n / [2] [3]) (symbol C or Cyt) is one of the four nucleotide bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group ...

  3. Sense (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Sense_(molecular_biology)

    An individual strand of DNA is referred to as positive-sense (also positive (+) or simply sense) if its nucleotide sequence corresponds directly to the sequence of an RNA transcript which is translated or translatable into a sequence of amino acids (provided that any thymine bases in the DNA sequence are replaced with uracil bases in the RNA ...

  4. Nucleic acid double helix - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_double_helix

    The DNA double helix biopolymer of nucleic acid is held together by nucleotides which base pair together. [3] In B-DNA, the most common double helical structure found in nature, the double helix is right-handed with about 10–10.5 base pairs per turn. [4] The double helix structure of DNA contains a major groove and minor groove.

  5. Nucleic acid sequence - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_sequence

    Nucleic acids consist of a chain of linked units called nucleotides. Each nucleotide consists of three subunits: a phosphate group and a sugar (ribose in the case of RNA, deoxyribose in DNA) make up the backbone of the nucleic acid strand, and attached to the sugar is one of a set of nucleobases.

  6. DNA-binding metallo-intercalators - Wikipedia

    en.wikipedia.org/wiki/DNA-Binding_Metallo-inter...

    DNA-binding metallo-intercalators are positively charged, planar, polycyclic, aromatic compounds that unwind the DNA double helix and insert themselves between DNA base pairs. [1] Metallo- intercalators insert themselves between two intact base pairs without expelling or replacing the original nitrogenous bases ; the hydrogen bonds between the ...

  7. Cationic liposome - Wikipedia

    en.wikipedia.org/wiki/Cationic_liposome

    Due to the overall positive charge of cationic liposomes, they interact with negatively charged cell membranes more readily than classic liposomes. [3] This positive charge can also create some issues in vivo , such as binding to plasma proteins in the bloodstream, which leads to opsonization. [ 5 ]

  8. Base pair - Wikipedia

    en.wikipedia.org/wiki/Base_pair

    The following DNA sequences illustrate pair double-stranded patterns. By convention, the top strand is written from the 5′-end to the 3′-end; thus, the bottom strand is written 3′ to 5′. A base-paired DNA sequence: ATCGATTGAGCTCTAGCG TAGCTAACTCGAGATCGC The corresponding RNA sequence, in which uracil is substituted for thymine in the RNA ...

  9. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    A nucleic acid sequence is the order of nucleotides within a DNA (GACT) or RNA (GACU) molecule that is determined by a series of letters. Sequences are presented from the 5' to 3' end and determine the covalent structure of the entire molecule.