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  2. What is gabapentin? Here's why it's so controversial. - AOL

    www.aol.com/news/gabapentin-heres-why...

    Gabapentin is a prescription medication that was approved by the U.S. Food and Drug Administration in 1993 as a treatment for epilepsy. It works by binding to a type of calcium channel in nerve ...

  3. Medication package insert - Wikipedia

    en.wikipedia.org/wiki/Medication_package_insert

    PILLS (Patient Information Language Localisation System) is a one-year effort by the European Commission to produce a prototype tool which will support the creation of various kinds of medical documentation simultaneously in multiple languages, by storing the information in a database and allowing a variety of forms and languages of output.

  4. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin does not bind to other drug transporters such as P-glycoprotein (ABCB1) or OCTN2 (SLC22A5). [95] It is not significantly bound to plasma proteins (<1%). [94] Gabapentin undergoes little or no metabolism. [86] [94] Gabapentin is generally safe in people with liver cirrhosis. [99] Gabapentin is eliminated renally in the urine. [94]

  5. Can Gabapentin Really Cause ED? - AOL

    www.aol.com/lifestyle/gabapentin-really-cause-ed...

    If you’re taking gabapentin for any number of reasons — seizures, neuropathic pain, etc. — you likely know what it does. But understandably, you could be confused about how a medication for ...

  6. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    Conversely, food increases the area-under-curve levels of gabapentin by about 10%. [24] Drugs that increase the transit time of gabapentin in the small intestine can increase its oral bioavailability; when gabapentin was co-administered with oral morphine (which slows intestinal peristalsis), [27] the oral bioavailability of a 600 mg dose of ...

  7. Anticonvulsant - Wikipedia

    en.wikipedia.org/wiki/Anticonvulsant

    Data from studies conducted on women taking antiepileptic drugs for non-epileptic reasons, including depression and bipolar disorder, show that if high doses of the drugs are taken during the first trimester of pregnancy then there is the potential of an increased risk of congenital malformations. [102]

  8. Neuropathic pain - Wikipedia

    en.wikipedia.org/wiki/Neuropathic_pain

    There is no predictor test to determine if it will be effective for a particular person. A short trial period of gabapentin therapy is recommended, to determine the effectiveness for that person. 62% of people taking gabapentin may have at least one adverse event, however the incidence of serious adverse events was found to be low. [26]

  9. Rectal administration - Wikipedia

    en.wikipedia.org/wiki/Rectal_administration

    Because using the rectal route enables a rapid, safe, and lower cost alternative to administration of medications, [5] it may also facilitate the care of patients in long-term care or palliative care, or as an alternative to intravenous or subcutaneous medication delivery in other instances.

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