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  2. Medication-related osteonecrosis of the jaw - Wikipedia

    en.wikipedia.org/wiki/Medication-related_osteo...

    Particular medications can result in MRONJ, a serious but uncommon side effect in certain individuals. Such medications are frequently used to treat diseases that cause bone resorption such as osteoporosis, or to treat cancer. The main groups of drugs involved are anti-resorptive drugs, and anti-angiogenic drugs.

  3. Acute radiation syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_radiation_syndrome

    Radiation causes cellular degradation by autophagy. Acute radiation syndrome ( ARS ), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. [ 1] Symptoms can start within an hour of exposure, and can last for ...

  4. Zoledronic acid - Wikipedia

    en.wikipedia.org/wiki/Zoledronic_acid

    Zoledronic acid, also known as zoledronate and sold under the brand name Zometa among others, [ 7] by Novartis among others, is a medication used to treat a number of bone diseases. [ 3] These include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, Paget's disease of bone [ 3] and Duchenne muscular dystrophy (DMD ...

  5. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Osteoporosis, including drug- and cancer-related osteoporosis, giant cell tumour of bone and hypercalcaemia of malignancies: Hypercholesterolaemia, cataract, urinary retention, hypocalcaemia, osteonecrosis of the jaw and anaphylaxis. Gemtuzumab ozogamicin: IV: CD33 antibody that induces apoptosis of the tagged cell. Acute myeloid leukaemia

  6. Bisphosphonate - Wikipedia

    en.wikipedia.org/wiki/Bisphosphonate

    Bisphosphonates are used to treat osteoporosis, osteitis deformans (Paget's disease of the bone), bone metastasis (with or without hypercalcemia), multiple myeloma, and other conditions involving fragile, breakable bone. In osteoporosis and Paget's, the most popular first-line bisphosphonate drugs are alendronate and risedronate.

  7. Osteonecrosis of the jaw - Wikipedia

    en.wikipedia.org/wiki/Osteonecrosis_of_the_jaw

    Osteonecrosis of the jaw ( ONJ) is a severe bone disease ( osteonecrosis) that affects the jaws (the maxilla and the mandible ). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature. Osteonecrosis of the jaw associated with bisphosphonate therapy, which is required by some cancer ...

  8. Teriparatide - Wikipedia

    en.wikipedia.org/wiki/Teriparatide

    Teriparatide is a portion of human parathyroid hormone (PTH), amino acid sequence 1 through 34, of the complete molecule (containing 84 amino acids). Endogenous PTH is the primary regulator of calcium and phosphate metabolism in bone and kidney. PTH increases serum calcium, partially accomplishing this by increasing bone resorption.

  9. Radiation therapy - Wikipedia

    en.wikipedia.org/wiki/Radiation_therapy

    Side effects are dose-dependent; for example, higher doses of head and neck radiation can be associated with cardiovascular complications, thyroid dysfunction, and pituitary axis dysfunction. [15] Modern radiation therapy aims to reduce side effects to a minimum and to help the patient understand and deal with side effects that are unavoidable.

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