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The formation of teeth begins during embryonic development and is a process that is highly regulated by various signaling pathways, which, if disrupted as a result of genetic mutations or environmental factors, can lead to developmental anomalies, including hyperdontia. Tooth development begins with the formation of tooth buds in the jaw.
Gingival enlargement has a multitude of causes. The most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by prolonged exposure to bacterial plaque, and is treated with conventional periodontal treatment, such as scaling and root planing.
A 2023 paper published in Regenerative Therapy decries the lack of treatments available for tooth regrowth, but highlights how the anti-USAG-1 antibody treatment in mice could offer “a ...
A set of human teeth under an orthopantomogram. Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.
A clinical trial is set to begin in 2024. For premium support please call: 800-290-4726 more ways to reach us
Treatment such as irradiation has been shown to have severe effects on developing teeth. In a smaller capacity, chemotherapy was also found to have a similar effect. Thalidomide (N-phthaloylglutamine) was also discovered to have a causative effect on mothers who took the drug during pregnancy, resulting in congenitally missing teeth in their ...
Their tendency to grow in size may also contribute to periodontal disease as a result of food build up in the area of the lesion. [ 11 ] Radiographically, buccal exostoses can be identified as round, well-defined structures which superimpose the roots of the teeth, normally in the premolar and molar region.
Periapical true cysts - cysts containing cavities entirely surrounded in epithelial lining. Resolution of this type of cyst requires surgical treatment such as a cystectomy. [10] Periapical pocket cysts - epithelium lined cavities that have an opening to the root canal of the affected tooth. Resolution may occur after traditional root canal ...
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