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Little is known about the biological activity and composition of marine fish venoms, due to the difficulties in obtaining, storing and extracting venom samples.The National University of Singapore performed the first purification of the stonefish venom, because stonefish stings have been responsible for a number of deaths and severe poisoning cases in the local area. [1]
The stonefish, Synanceia verrucosa, has a diverse set of toxins that disrupts basic human ability. When injected with the toxins found in the dorsal fins of the fish, individuals will suffer from skeletal muscle paralysis , extreme pain, seizures , convulsions , respiratory arrest , and damage to the cardiovascular system . [ 1 ]
Stonefish venom can be fatal at a dose of only 18 mg, which the fish is capable of releasing with only six of its thirteen spines. The protein makeup differs between the three species of stonefish, but in reef stonefish the fatal protein is the verrucotoxin protein. [15] Effects of the venom include severe pain, shock, paralysis, and tissue ...
Synanceia is a genus of ray-finned fish belonging to the subfamily Synanceiinae, the stonefish, which is classified within the family Scorpaenidae, the scorpionfish and relatives. Stonefish are the most venomous fish known; stings can be fatal to humans. [2] [3] They are found in the coastal regions of the Indo-Pacific.
Venomous fish are very often involved in human injury, usually by accident, but few studies have been done to investigate the constituents of fish venom. Even fewer studies have been done to create antivenom. The only commercially available antivenom is for the Indo-Pacific stonefish, Synanceja trachynis Stonefish Antivenom (SFAV). [17]
Future research should investigate the toxins role in predator defence, parasite prevention, and mitigating epibiosis. Further inquiry into stonefish toxins would expand ecological insights and may reveal therapeutic and industrial potential Antivenom is available for stonefish stings. [5]
Synanceiinae, or the family Synanceiidae, was first named and recognised as a grouping of related taxa by the English naturalist William Swainson in 1839. [1] The 5th edition of Fishes of the World treats this grouping as a subfamily within the family Scorpaenidae, dividing the subfamily into the three tribes: Minoini, Choridactylini and Synanceiini. [3]
Synanceia nana, the Red Sea stonefish or dwarf scorpionfish, is a species of venomous, marine ray-finned fish, a stonefish belonging to the subfamily Synanceiinae which is classified as being within the family Scorpaenidae, the scorpionfishes and their relatives. It is found in the northwestern Indian Ocean.