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Before effective treatments were available, syphilis could sometimes be disfiguring in the long term, leading to defects of the face and nose ("nasal collapse"). Syphilis was a stigmatized disease due to its sexually transmissible nature. Such defects marked the person as a social pariah, and a symbol of sexual deviancy.
During the 20th century, as both microbiology and pharmacology advanced greatly, syphilis, like many other infectious diseases, became more of a manageable burden than a scary and disfiguring mystery, at least in developed countries among those people who could afford to pay for timely diagnosis and treatment. Penicillin was discovered in 1928 ...
Arsphenamine, also known as Salvarsan or compound 606, is an antibiotic drug that was introduced at the beginning of the 1910s as the first effective treatment for the deadly infectious diseases syphilis, relapsing fever, and African trypanosomiasis. [2] [3] This organoarsenic compound was the first modern antimicrobial agent. [4]
Penicillin also halted the development of chronic conditions caused by untreated syphilis that appeared decades after infection. General paresis ( neurosyphilis ) once accounted for up to 25 ...
A poster encouraging premarital syphilis blood tests, created shortly before New York state began mandating premarital testing in July 1938. [ 8 ] A wave of more effective laws requiring blood tests for both partners were passed by state legislatures between 1935 and 1950, beginning with Connecticut's "premarital examination law", which served ...
The preferred antibiotic treatment for syphilis is in short supply across the United States as infections soar, and more than three dozen leading public health groups are urging the White House to ...
Salvarsan was commercially introduced in 1910, and in 1913, a less toxic form, "Neosalvarsan" (Compound 914), was released in the market. These drugs became the principal treatments of syphilis until the arrival of penicillin and other novel antibiotics towards the middle of the 20th century. [7]
The first effective treatment for a sexually transmitted infection was salvarsan, a treatment for syphilis. With the discovery of antibiotics, a large number of sexually transmitted infections became easily curable, and this, combined with effective public health campaigns against STIs, led to a public perception during the 1960s and 1970s that ...
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