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However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta. Due to this, there is an increased risk for intrauterine growth retardation, fetal hemorrhage, and maternal hemorrhage within organogenesis and in the second/third trimester. [ 12 ]
SSRIs do not appear to affect the risk of coronary heart disease (CHD) in those without a previous diagnosis of CHD. [89] A large cohort study suggested no substantial increase in the risk of cardiac malformations attributable to SSRI usage during the first trimester of pregnancy. [90]
Fluoxetine taken during pregnancy is associated with a significant increase in congenital heart defects in newborns. [12] [13] It has been suggested that fluoxetine therapy may be continued during breastfeeding if it was used during pregnancy or if other antidepressants were ineffective. [14]
A new Canadian study suggests that women who take antidepressants during pregnancy may be more likely to give birth to children with autism.
For many antidepressants, this risk is highest during the first few weeks and months of treatment. ... but that there is insufficient study data regarding its effects on a human fetus during ...
Treatments for drug addiction during pregnancy are safe for both the mother and the baby, doctors say. ... "This has led to many women either deciding to not start life-saving medication during ...
Use during pregnancy and breastfeeding is not generally recommended. [7] It is in the serotonin modulator class of medications and is believed to work both as an SSRI and activator of the 5-HT 1A receptor. [1] Vilazodone was approved for medical use in the United States in 2011 [1] and in Canada in 2018. [8]
Antidepressant exposure is not associated with an increased risk of spontaneous abortion. [55] There is a tentative association of SSRI use during pregnancy with heart problems in the baby. [56] The advantages of their use during pregnancy may thus not outweigh the possible negative effects on the baby. [56]