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Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
The concern goes beyond ineffectiveness; phenylephrine can come with side effects such as headaches, insomnia and nervousness. At higher doses, it can increase blood pressure.
Do over-the-counter decongestants like Sudafed PE work? Doctors have said oral phenylephrine is ineffective to relieve nasal congestion. An FDA panel will reevaluate the evidence.
As Yahoo Life reported last year, when taken in oral form, phenylephrine is metabolized so quickly that the amount absorbed into the bloodstream ends up being less than 1% of what was originally ...
Phenylephrine, which alongside paracetamol is one of Lemsip's two primary active ingredients and is intended to be responsible for most of the product's claimed effects, was discovered to be ineffective as a decongestant in 2015, leading some pharmacists to call for the ingredient to be banned. [4]
Phenylpropanolamine (PPA), sold under many brand names, is a sympathomimetic agent which is used as a decongestant and appetite suppressant. [9] [1] [10] [11] It was previously commonly used in prescription and over-the-counter cough and cold preparations.
The panel vote could lead to the removal of oral phenylephrine, which is a major component of popular products like Benadryl, Advil and Tylenol, from the FDA's list of approved OTC ingredients ...
Side effects of etilefrine include nausea, tremors, and palpitations, among others. [5] Etilefrine is an agonist of the α-and β-adrenergic receptors. [6] It is a substituted phenethylamine and is related to epinephrine, phenylephrine, and norfenefrine. [2] Etilefrine was first described and introduced for medical use by 1949. [7] [8]