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2-Chloromethylpyridine is an organohalide that consists of a pyridine core bearing a chloromethyl group. It is one of three isomeric chloromethylpyridines, along with 3- and 4-chloromethylpyridine. It is an alkylating agent. 2-Chloromethylpyridine is a precursor to pyridine-containing ligands. [1] [2]
Heating the reaction intermediate with 2-chloro-5-(chloromethyl)pyridine in THF under reflux yields flupyradifurone. [2] In the second method, tetronic acid, 4-touluenesulfonic acid, and N -[(6-chloropyridin-3-yl)methyl]-2,2-difluoroethane-1-amine in toluene are heated under reflux for 2 hours to produce flupyradifurone.
In these conversions, chloride is displaced. [2] Pyrithione, the conjugate base of 2-mercaptopyridine-N-oxide, is a fungicide found in some shampoos. Oxidation 2-chloropyridine gives 2-chloropyridine-N-oxide. [5] The antihistamine pheniramine may be generated via the reaction of phenylacetonitrile with 2-chloropyridine in the presence of a base ...
Structure of the chloromethyl group. In organic chemistry, the chloromethyl group is a functional group that has the chemical formula −CH 2 −Cl. The naming of this group is derived from the methyl group (which has the formula −CH 3), by replacing one hydrogen atom by a chlorine atom. Compounds with this group are a subclass of the ...
Direct halogenation of pyridine with chlorine gas above 270 °C gives a mixture of 2-chloropyridine and 2,6-dichloropyridine. [1] 2- and 4-chloropyridine are prepared from the corresponding pyridinols using phosphoryl chloride. [1]
December 12, 2024 at 5:30 AM This Nighttime Behavior Can Be A Sign Of Dementia skynesher - Getty Images There are plenty of reason you might feel off in the late afternoon and evening.
The third book in the Yarros’ “Empyrean” series comes out in January from Entangled Publishing. The follow-up to “Fourth Wing” and “Iron Flame” swaps Basgiath War College lessons for ...
Dichloropyridines are organic compounds with the formula Cl 2 C 5 H 3 N, consisting of a pyridine ring substituted with two ... 26452-80-2-1 2,5-Dichloropyridine ...