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Most Ig domains are either variable (IgV) or constant (IgC). IgV: IgV domains with 9 beta strands are generally longer than IgC domains with 7 beta strands. IgC1 and IgC2: Ig domains of some members of the IgSF resemble IgV domains in the amino acid sequence, yet are similar in size to IgC domains. These are called IgC2 domains, while standard ...
The immunoglobulin domain, also known as the immunoglobulin fold, is a type of protein domain that consists of a 2-layer sandwich of 7-9 antiparallel β-strands arranged in two β-sheets with a Greek key topology, [1] [2] consisting of about 125 amino acids. The backbone switches repeatedly between the two β
Each antibody binds to a specific antigen in a highly specific interaction analogous to a lock and key.. An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that cause disease.
The fact that there is no standard definition of what a domain really is has meant that domain assignments have varied enormously, with each researcher using a unique set of criteria. [ 67 ] A structural domain is a compact, globular sub-structure with more interactions within it than with the rest of the protein. [ 68 ]
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Istituto di Genetica Vegetale (IGV) is a research network om Plant Genetics and Breeding within the Italian Consiglio Nazionale delle Ricerche (National Research Council). IGV is headquartered in Bari and has four different Divisions in Portici, Palermo, Florence and Perugia. IGV started its activities in November 2002.
A factsheet or fact sheet, also called fact file, is a single-page document containing essential information about a product, substance, service or other topic. Factsheets are frequently used to provide information to an end user , consumer or member of the public in concise, simple language.
Orthoebolavirus zairense [1] or Zaire ebolavirus, more commonly known as Ebola virus (/ i ˈ b oʊ l ə, ɪ-/; EBOV), is one of six known species within the genus Ebolavirus. [2] Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD).
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