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Carbon tetrachloride, also known by many other names (such as carbon tet for short and tetrachloromethane, also recognised by the IUPAC), is a chemical compound with the chemical formula CCl 4. It is a non-flammable, dense, colourless liquid with a "sweet" chloroform-like odour that can be detected at low levels.
A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver.. It can be a side-effect, but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids, or in laboratory environments, such as carbon tetrachloride, or far more pervasively in the form of ethanol (drinking alcohol).
Carbon tetrachloride is commonly used to induce acute type A liver injury in animal models. Idiosyncratic (type B) injury occurs without warning, when agents cause non-predictable hepatotoxicity in susceptible individuals, which is not related to dose and has a variable latency period. [ 8 ]
Chloroform undergoes further chlorination to yield carbon tetrachloride (CCl 4): CHCl 3 + Cl 2 → CCl 4 + HCl The output of this process is a mixture of the four chloromethanes: chloromethane , methylene chloride (dichloromethane), trichloromethane (chloroform), and tetrachloromethane (carbon tetrachloride).
This was a problem as carbon tetrachloride is an effective fire suppressant and was formerly in widespread use in fire extinguishers. [15] There are reports of fatalities caused by its use to fight fires in confined spaces. [16] Carbon tetrachloride's generation of phosgene and its own toxicity mean it is no longer used for this purpose. [15]
The handling of this chemical may incur notable safety precautions. It is highly recommend that you seek the Material Safety Datasheet for this chemical from a reliable source such as SIRI, and follow its directions.
Novak Djokovic is speaking out about how he believes he got food poisoning during his 2022 detention in Melbourne, Australia.. In a new February 2025 cover interview with GQ published Thursday ...
Side products include carbon tetrachloride, hydrogen chloride, and hexachlorobutadiene. Several other methods have been developed. When 1,2-dichloroethane is heated to 400 °C with chlorine, tetrachloroethylene is produced: ClCH 2 CH 2 Cl + 3 Cl 2 → Cl 2 C=CCl 2 + 4 HCl