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FDG is used to explore the possibility of cancer spreading to other body sites (cancer metastasis). These FDG PET scans for detecting cancer metastasis are the most common in standard medical care (representing 90% of current scans). The same tracer may also be used for the diagnosis of types of dementia.
Carbon-11 choline has found more success in cancer systems imaging. Choline is a precursor for the synthesis of phospholipids. [4] When a cell is about to divide, it synthesizes these phospholipids to generate enough material to build the cell membranes of the two daughter cells. Thus it was hypothesized that highly proliferative tumors would ...
[13] [23] Hence, 68 Ga-Trivehexin can be used for PET imaging of αvβ6-integrin positive cancers (i.e., those whose cells possess a sufficiently high density of αvβ6 on their surface), including but not limited to pancreatic ductal adenocarcinoma, [24] non-small cell lung cancer, squamous cell carcinomas (SCC) of different origin (most ...
PET is a functional imaging technique that produces a three-dimensional image of functional processes in the body. The system detects pairs of gamma rays emitted indirectly by a positron -emitting radionuclide ( tracer ), which is introduced into the body on a biologically active molecule.
Diagnostically the increased glucose consumption by cancer cells resulting from the Warburg effect is the basis for tumor detection in a PET scan, in which an injected radioactive glucose analog is detected at higher concentrations in malignant cancers than in other tissues.
In PET imaging, [18 F]FDG is primarily used for imaging tumors in oncology, where a static [18 F]FDG PET scan is performed and the tumor [18 F]FDG uptake is analyzed in terms of Standardized Uptake Value (SUV). FDG PET/CT can be used for the assessment of glucose metabolism in the heart and the brain.
Imaging joint inflammation in an arthritic mouse using positron emission tomography. PET, MRI, and overlaid images of a human brain. Positron emission tomography (PET) is a nuclear medicine imaging technique which produces a three-dimensional image or picture of functional processes in the body. The theory behind PET is simple enough.
CT scan (left) and gallium PSMA PET scan (right) of patient with prostate cancer metastases in the bones. The positron emitting isotope, 68 Ga, can be used to target prostate-specific membrane antigen (PSMA), a protein which is present in prostate cancer cells.
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