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[4] [3] As such, testosterone cypionate and testosterone enanthate are considered to be "functionally interchangeable" as medications. [4] For reference, testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days and requires frequent administration of approximately once per week. [21]
Testosterone cypionate: Depo-Testosterone: Oil solution: 50–250 mg 1x/1–4 weeks Testosterone isobutyrate: Agovirin Depot: Aqueous suspension: 50–100 mg 1x/1–2 weeks Testosterone phenylacetate b: Perandren, Androject: Oil solution: 50–200 mg 1×/3–5 weeks Mixed testosterone esters: Sustanon 100, Sustanon 250: Oil solution: 50–250 ...
Pharmacokinetics of testosterone esters Testosterone ester Form Route T max Tooltip Time to peak levels t 1/2 Tooltip Elimination half-life MRT Tooltip Mean residence time; Testosterone undecanoate: Oil-filled capsules: Oral? 1.6 hours: 3.7 hours Testosterone propionate: Oil solution: Intramuscular injection? 0.8 days: 1.5 days Testosterone ...
Testosterone esters were synthesized for the first time in 1936, and were found to have greatly improved potency relative to testosterone. [12] Among the esters synthesized, testosterone propionate was the most potent, and for this reason, was selected for further development, subsequently being marketed. [ 12 ]
The following major testosterone ester has not been marketed: [1] [2] Testosterone buciclate (20 Aet-1, CDB-1781) – a very long-acting testosterone ester that was under development but ultimately did not reach the market [4] [5] And the following less commonly known testosterone esters have also not been marketed: [1] [2]
Structural properties of major testosterone esters; Androgen Structure Ester Relative mol. weight Relative T content b logP c; Position(s) Moiet(ies) Type Length a; Testosterone – – – – 1.00
Caesium in the body has a biological half-life of about one to four months. Mercury (as methylmercury) in the body has a half-life of about 65 days. Lead in the blood has a half life of 28–36 days. [29] [30] Lead in bone has a biological half-life of about ten years. Cadmium in bone has a biological half-life of about 30 years.
Testosterone undecanoate has a very long elimination half-life and mean residence time when given as a depot intramuscular injection. [27] [7] [8] Its elimination half-life is 20.9 days and its mean residence time is 34.9 days in tea seed oil, while its elimination half-life is 33.9 days and its mean residence time is 36.0 days in castor oil.