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  2. Regulation of gene expression - Wikipedia

    en.wikipedia.org/wiki/Regulation_of_gene_expression

    Regulation of gene expression by a hormone receptor Diagram showing at which stages in the DNA-mRNA-protein pathway expression can be controlled. Regulation of gene expression, or gene regulation, [1] includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA).

  3. Gene regulatory network - Wikipedia

    en.wikipedia.org/wiki/Gene_regulatory_network

    Structure of a gene regulatory network Control process of a gene regulatory network. A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell.

  4. Regulator gene - Wikipedia

    en.wikipedia.org/wiki/Regulator_gene

    A regulator gene may encode a protein, or it may work at the level of RNA, as in the case of genes encoding microRNAs. An example of a regulator gene is a gene that codes for a repressor protein that inhibits the activity of an operator (a gene which binds repressor proteins thus inhibiting the translation of RNA to protein via RNA polymerase). [1]

  5. Regulatory sequence - Wikipedia

    en.wikipedia.org/wiki/Regulatory_sequence

    Regulation of transcription in mammals. An active enhancer regulatory sequence of DNA is enabled to interact with the promoter DNA regulatory sequence of its target gene by formation of a chromosome loop. This can initiate messenger RNA (mRNA) synthesis by RNA polymerase II (RNAP II) bound to the promoter at the transcription start site of the ...

  6. Genetics - Wikipedia

    en.wikipedia.org/wiki/Genetics

    This is an accepted version of this page This is the latest accepted revision, reviewed on 27 January 2025. Science of genes, heredity, and variation in living organisms This article is about the general scientific term. For the scientific journal, see Genetics (journal). For a more accessible and less technical introduction to this topic, see Introduction to genetics. For the Meghan Trainor ...

  7. Cis-regulatory element - Wikipedia

    en.wikipedia.org/wiki/Cis-regulatory_element

    Cis-regulatory elements (CREs) or cis-regulatory modules (CRMs) are regions of non-coding DNA which regulate the transcription of neighboring genes.CREs are vital components of genetic regulatory networks, which in turn control morphogenesis, the development of anatomy, and other aspects of embryonic development, studied in evolutionary developmental biology.

  8. Enhancer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Enhancer_(genetics)

    Among this constellation of elements, enhancers and their associated transcription factors have a leading role in the regulation of gene expression. [31] An enhancer localized in a DNA region distant from the promoter of a gene can have a very large effect on gene expression, with some genes undergoing up to 100-fold increased expression due to ...

  9. Silencer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Silencer_(genetics)

    DNA gene structure of a eukaryote. In genetics, a silencer is a DNA sequence capable of binding transcription regulation factors, called repressors.DNA contains genes and provides the template to produce messenger RNA (mRNA).