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The symptoms of an episode of diabetic ketoacidosis usually evolve over a period of about 24 hours. Predominant symptoms are nausea and vomiting, pronounced thirst, excessive urine production and abdominal pain that may be severe. [13] [14] In severe DKA, breathing becomes rapid and of a deep, gasping character, called "Kussmaul breathing".
The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.
Ketoacidosis is a metabolic state caused by uncontrolled production of ketone bodies that cause a metabolic acidosis.While ketosis refers to any elevation of blood ketones, ketoacidosis is a specific pathologic condition that results in changes in blood pH and requires medical attention.
The effects of sustaining ketosis for up to two years are known from studies of people following a strict ketogenic diet for epilepsy or type 2 diabetes; these include short-term adverse effects leading to potential long-term ones. [20] However, literature on longer term effects of intermittent ketosis is lacking. [20]
Diabetic ketoacidosis, a life-threatening complication that happens due to increased ketones in the blood ... first-line medications for type 2 diabetes. Side effects of diabetes medications can ...
Ketoacidosis (e.g., Diabetic, alcoholic, or starvation) [15] Chronic kidney failure [16] 5-oxoprolinemia due to long-term ingestion of high-doses of acetaminophen with glutathione depletion [17] (often seen with sepsis, liver failure, kidney failure, or malnutrition [citation needed]) Intoxication: Salicylates, methanol, ethylene glycol [15]
Once ketotic hypoglycemia has been diagnosed and other conditions excluded, long-term management aims to reduce the frequency and duration of episodes. [8] Extended fasts should be avoided. [ 2 ] [ 1 ] Children should be given a bedtime snack rich in carbohydrates and should be awakened and fed after the usual duration of sleep.
Some severe side effects with long-term consequences may include pancreatitis, acute kidney injury, gallstones, gallbladder disease, diabetic retinopathy, and an increased heart rate. Semaglutide ...