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Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [5]
However, this medication isn’t recommended for long-term use, as it can cause dependence, become less effective over time and lead to withdrawal symptoms when stopped.
Sertraline has been used since the 1990s by tens of millions of people, and in that time there have been no established side effects specific to long-term use. That’s not to say that long-term ...
This technique may be used if your medication puts you at risk for withdrawal symptoms, which may occur when some antidepressants are stopped without a gradual taper. Taper and moderate switch.
Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [10] The effectiveness of sertraline for depression is similar to that of other antidepressants such as Fluoxetine or Paroxetine. Sertraline is better tolerated than the older tricyclic antidepressants.
Symptoms typically persist for a longer time frame in patients taking drugs which have a long elimination half-life, active metabolites, or a protracted duration of action. [ 6 ] Cases have reported persisting chronic symptoms, [ 75 ] and antidepressant discontinuation may contribute to ongoing features. [ 76 ]
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It is considered a distinct phenomenon from antidepressant discontinuation syndrome, post-acute withdrawal syndrome, and major depressive disorder, [70] [68] and should be distinguished from sexual dysfunction associated with depression [70] and persistent genital arousal disorder. [64]