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Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [5]
The withdrawal symptoms for sertraline are less severe and frequent than for paroxetine, and more frequent than for fluoxetine. [86] [87] In most cases symptoms are mild, short-lived, and resolve without treatment. More severe cases are often successfully treated by temporary reintroduction of the drug with a slower tapering-off rate. [88]
Abruptly stopping sertraline before your next dose could lead to uncomfortable withdrawal symptoms, including eye pain, nausea, headaches, irritability, nightmares or frequent thoughts about death.
Or maybe you’re more familiar with the names Lexapro, Zoloft or Prozac. ... Withdrawal symptoms. Abruptly stopping medications like SSRIs or other antidepressants can lead to withdrawal symptoms.
Upon the discontinuation of serotonergic drugs, most cases of SS resolve within 24 hours, [6] [9] [73] [74] although in some cases delirium may persist for a number of days. [31] Symptoms typically persist for a longer time frame in patients taking drugs which have a long elimination half-life , active metabolites, or a protracted duration of ...
The analysis also found that severe discontinuation symptoms, which might cause patients to drop out of a study or resume taking antidepressants, occurred in about 3% — or one in 35 — of those ...
Paroxetine may produce discontinuation-related symptoms at a greater rate than other SSRIs, though qualitatively similar effects have been reported for all SSRIs. [ 181 ] [ 182 ] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from ...
SSRIs are modern antidepressants often used as a first-line treatment for major depressive disorder. Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram ...