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Still, another form of illness called chronic refractory cough doesn’t respond to treatment. It involves cough nerves that are hypersensitive to triggers that don’t make others cough, such as ...
[1] [8] Chronic cough is a common symptom in several different respiratory diseases like COPD or pulmonary fibrosis [9] but in non-smokers with a normal chest x-ray chronic cough are often associated with asthma, rhinosinusitis, and gastroesophageal reflux disease or could be idiopathic.
The health regulator concluded the company's application for the drug, gefapixant, did not meet substantial evidence of effectiveness for treating refractory chronic cough and unexplained chronic ...
Merck's (MRK) two phase III studies on gefapixant (MK-7264) for the treatment of refractory or unexplained chronic cough meet the primary efficacy endpoints.
Gefapixant, sold under the brand name Lyfnua, is a medication used to treat chronic (long-term) cough. [1] It acts as an antagonist of the P2RX3 receptor. [2] [3] [4] It was approved for medical use in the European Union in September 2023. [1]
A postinfectious cough is a lingering cough that follows a respiratory tract infection, such as a common cold or flu and lasting up to eight weeks. Postinfectious cough is a clinically recognized condition represented within the medical literature.
Merck's (MRK) new drug application for gefapixant to treat refractory chronic cough or unexplained chronic cough fails to secure approval from the FDA. Meanwhile, the drug secures approval in Japan.
A habit cough is a chronic cough that has no underlying organic cause or medical diagnosis, [1] [2] and does not respond to conventional medical treatment. [3] This is sometimes called tic cough, somatic cough syndrome and previously psychogenic cough, but without clinical justification.
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