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Fatigue is a state of tiredness (which is not sleepiness), exhaustion [1] or loss of energy. [2] [3]Fatigue (in the medical sense) is sometimes associated with medical conditions including autoimmune disease, organ failure, chronic pain conditions, mood disorders, heart disease, infectious diseases, and post-infectious-disease states. [4]
[1] [page needed] Directed attention fatigue occurs when a particular part of the brain's global inhibitory system is overworked due to the suppression of increasing numbers of stimuli. This temporary condition is not a clinical illness or a personality disorder. It is rather a temporary fatigue of the inhibitory mechanisms in the brain.
“There’s a lot happening at once, and the brain needs to shift between all of those things.” Making things even worse is that a lot of these meetings can be crammed into one day, Hafeez says.
S.M., sometimes referred to as SM-046, is an American woman with a peculiar type of brain damage that physiologically reduces her ability to feel fear.First described by scientists in 1994, [1] she has had exclusive and complete bilateral amygdala destruction since late childhood as a consequence of Urbach–Wiethe disease.
In the brain, serotonin is a neurotransmitter and regulates arousal, behavior, sleep, and mood, among other things. [9] During prolonged exercise where central nervous system fatigue is present, serotonin levels in the brain are higher than normal physiological conditions; these higher levels can increase perceptions of effort and peripheral muscle fatigue. [9]
Traumatic brain injury is defined as damage to the brain resulting from external mechanical force, such as rapid acceleration or deceleration, impact, blast waves, or penetration by a projectile. [10] Brain function is temporarily or permanently impaired and structural damage may or may not be detectable with current technology. [11]
Repeated exposure to the same topic in the media over a long period of time has shown to cause psychological fatigue. [1] While psychological fatigue has no singular definition, it can be characterized by negative emotions such as stress, overwhelm, strain, and sensory overload.
Cerebral contusion (Latin: contusio cerebri), a form of traumatic brain injury, is a bruise of the brain tissue. [2] Like bruises in other tissues, cerebral contusion can be associated with multiple microhemorrhages, small blood vessel leaks into brain tissue. Contusion occurs in 20–30% of severe head injuries. [3]