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The disease consists of persistent low-grade fever, chest pain (usually pleuritic), pericarditis (usually evidenced by a pericardial friction rub, chest pain worsening when recumbent, and diffuse ST elevation with PR segment depression), and/or pericardial effusion. The symptoms tend to occur 2–3 weeks after myocardial infarction but can also ...
Complications can include cardiac tamponade, myocarditis, and constrictive pericarditis. [1] [2] Pericarditis is an uncommon cause of chest pain. [9] About 3 per 10,000 people are affected per year. [2] Those most commonly affected are males between the ages of 20 and 50. [10] Up to 30% of those affected have more than one episode. [10]
Although no current drug on the market prevents post-pericardiotomy syndrome, colchicine seems to provide an effective and safe way to treat pericarditis by reducing inflammation. [6] Colchicine is a natural product extracted from plants, and is a secondary metabolite (an organic compound not directly related to growth and development in an ...
The onset of purulent pericarditis is usually acute, with most individuals presenting to a medical facility approximately 3 days following the onset of symptoms. [4] As a subtype of pericarditis, purulent pericarditis often presents with substernal chest pain that is exacerbated by deep breathing and lying in the supine position. [5]
Pericardiectomy is the surgical removal of part or most of the pericardium. [1] [2] This operation is most commonly used to relieve constrictive pericarditis, or to remove a pericardium that is calcified and fibrous. [2] It may also be used for severe or recurrent cases of pericardial effusion. [3]
The pericardium, the double-walled sac surrounding the heart, consists of a fibrous pericardium layer on the outside and a double-layered serous pericardium on the inside. [18] Between the two layers of the serous pericardium is the pericardial space, which is filled with lubricating serous fluid that prevents friction as the heart contracts. [19]
The cause of constrictive pericarditis in the developing world are idiopathic in origin, though likely infectious in nature. In regions where tuberculosis is common, it is the cause in a large portion of cases. [3] Causes of constrictive pericarditis include: Tuberculosis [4] Incomplete drainage of purulent pericarditis [4] Fungal and parasitic ...
In 1983, an incidence of myocarditis of 1 per 10 000 was reported among Finnish military personnel. [4] Among US military service members vaccinated between December 2002 and March 2003 with Dryvax smallpox vaccine 18 cases of probable myopericarditis were reported, which was an incidence of 7.8 per 100 000 over 30 days.
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