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In South Africa, ephedrine was moved to schedule 6 on 27 May 2008, [84] which makes pure ephedrine tablets prescription only. Pills containing ephedrine up to 30 mg per tablet in combination with other medications are still available OTC, schedule 1 and 2, for sinus, head colds, and influenza.
Guaifenesin is an oral medication used to try to help cough out phlegm from the airways. [1] It is often used in combination with other medications. [1] It is believed to work by making airway secretions more liquid. [1] Side effects may include dizziness, sleepiness, skin rash, and nausea. [2] Guaifenesin has been used medically since at least ...
Guaifenesin is used in combination with, for example, ketamine, since guaifenesin does not provide analgesia or produce unconsciousness. [26] [27] In horses, the drug's biological half-life is 77 minutes. Premedication with xylazine (1.1 mg/kg) can reduce the dose required from 163 mg/kg (in geldings) to just 88 mg/kg. [27]
In December 2016, 20 American attorneys general filed a civil complaint accusing Aurobindo Pharma of a coordinated scheme to artificially maintain high prices for a generic antibiotic and diabetes drug. The complaint alleged price collusion schemes between six pharmaceutical firms including informal gatherings, telephone calls, and text ...
Examples are ephedrine, phenylephrine, pseudoephedrine, and oxymetazoline. Fever or pain medication. Examples are paracetamol (acetaminophen) and NSAIDs such as ibuprofen or naproxen. Also employed are various substances supposed to soften the coughing, like honey or supplement syrup. An example combination is guaifenesin with codeine.
200 mg, 400 mg, 600 mg (Rx only) Iceland Kratalgin: Austria Lotem: South Africa Medicol: Philippines Midol: Liquid Gels: 200 mg: USA [3] Moment: Italy Motrin: tablets, chewable tablets, oral suspension. 50 mg, 100 mg, 200 mg: Canada, [3] North Macedonia, USA [3] Mypaid: South Africa Myprodol: South Africa Narfen: South Korea Naron Ace: Japan ...
Guaifenesin protocol is an unapproved treatment for fibromyalgia suggested in the 1990s by R. Paul St. Amand, M.D. The protocol involves three parts: titrating the guaifenesin dosage, avoiding salicylates , and following a low-carbohydrate diet if the patient is hypoglycemic .
Low IC 50 or high pIC 50 values indicate tighter binding (pIC 50 of 8.0 = IC 50 of 10nM, pIC 50 of 9.0 = IC 50 of 1nM, etc.) These are non subtype selective IC 50 values averaged across all GABA A receptor subtypes , so subtype selective compounds with strong binding at one subtype but weak at others will appear unusually weak due to averaging ...