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  2. Chromosome segregation - Wikipedia

    en.wikipedia.org/wiki/Chromosome_segregation

    Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This segregation process occurs during both mitosis and meiosis. Chromosome segregation also occurs in prokaryotes ...

  3. Mitosis - Wikipedia

    en.wikipedia.org/wiki/Mitosis

    Because each resultant daughter cell should be genetically identical to the parent cell, the parent cell must make a copy of each chromosome before mitosis. This occurs during the S phase of interphase. [33] Chromosome duplication results in two identical sister chromatids bound together by cohesin proteins at the centromere.

  4. Sister chromatids - Wikipedia

    en.wikipedia.org/wiki/Sister_chromatids

    The two sister chromatids are separated from each other into two different cells during mitosis or during the second division of meiosis. Compare sister chromatids to homologous chromosomes, which are the two different copies of a chromosome that diploid organisms (like humans) inherit, one from each parent. Sister chromatids are by and large ...

  5. Chromosomal crossover - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_crossover

    Crossing over occurs between prophase I and metaphase I and is the process where two homologous non-sister chromatids pair up with each other and exchange different segments of genetic material to form two recombinant chromosome sister chromatids. It can also happen during mitotic division, [1] which may result in loss of heterozygosity.

  6. Genetic recombination - Wikipedia

    en.wikipedia.org/wiki/Genetic_recombination

    Most recombination occurs naturally and can be classified into two types: (1) interchromosomal recombination, occurring through independent assortment of alleles whose loci are on different but homologous chromosomes (random orientation of pairs of homologous chromosomes in meiosis I); & (2) intrachromosomal recombination, occurring through ...

  7. Spindle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Spindle_checkpoint

    Three types of cell division: binary fission (taking place in prokaryotes), mitosis and meiosis (taking place in eukaryotes).. When cells are ready to divide, because cell size is big enough or because they receive the appropriate stimulus, [20] they activate the mechanism to enter into the cell cycle, and they duplicate most organelles during S (synthesis) phase, including their centrosome.

  8. Establishment of sister chromatid cohesion - Wikipedia

    en.wikipedia.org/wiki/Establishment_of_sister...

    The proteins encoded by these genes all function in the chromosome cohesion pathway that is employed in the cohesion of sister chromatids during mitosis, DNA repair, chromosome segregation and the regulation of developmental gene expression. Defects in these functions likely underlie many of the features of Cornelia de Lang Syndrome.

  9. Prophase - Wikipedia

    en.wikipedia.org/wiki/Prophase

    Meiosis involves two rounds of chromosome segregation and thus undergoes prophase twice, resulting in prophase I and prophase II. [12] Prophase I is the most complex phase in all of meiosis because homologous chromosomes must pair and exchange genetic information. [3]: 98 Prophase II is very similar to mitotic prophase. [12]