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Optical coherence tomogram of a fingertip. It is possible to observe the sweat glands, having "corkscrew appearance" Interferometric reflectometry of biological tissue, especially of the human eye using short-coherence-length light (also referred to as partially-coherent, low-coherence, or broadband, broad-spectrum, or white light) was investigated in parallel by multiple groups worldwide ...
Medical optical imaging is the use of light as an investigational imaging technique for medical applications, pioneered by American Physical Chemist Britton Chance.Examples include optical microscopy, spectroscopy, endoscopy, scanning laser ophthalmoscopy, laser Doppler imaging, optical coherence tomography, and transdermal optical imaging.
Endomicroscopy is a technique for obtaining histology-like images from inside the human body in real-time, [1] [2] [3] a process known as ‘optical biopsy’. [4] [5] It generally refers to fluorescence confocal microscopy, although multi-photon microscopy and optical coherence tomography have also been adapted for endoscopic use.
Data published in late 2016 showed that over 150,000 intracoronary optical coherence tomography procedures are performed every year, and its adoption is rapidly growing at a rate of ~10-20% every year. [19] Assessment of artery lumen morphology is the cornerstone of intravascular imaging criteria to evaluate disease severity and guide intervention.
For FA, this corresponds to an excitation wavelength of blue (around 470 nm) and an emission wavelength near yellow (520 nm). [49] For IGCA, the newer method, the excitation wavelength is between 750 and 800 nm while emission occurs above 800 nm.
Dual-axis architecture with coherence imaging was introduced in the early 2010s. Prior to the development of DA-OCT, the dual-axis design was commonly used with multiple-scattering multispectral low coherence interferometry (ms2/LCI), a technique that also analyzes multiply scattered light to take depth-resolved images from optical scattering ...
Optical coherence tomography (OCT) represents a powerful clinical tool for monitoring retinal physiology in patients. OCT uses low coherence interferometry to differentiate tissues within the eye and create a cross section of a living patients’ retina non-invasively. [21] It actually has greater axial resolution than AOSLO. [22]
Optical coherence tomography angiography (OCTA) and Fluorescein angiography to visualize the vascular networks of the retina and choroid. Electroretinography (ERG) measures the electrical responses of various cell types in the retina , including the photoreceptors ( rods and cones ), inner retinal cells ( bipolar and amacrine cells), and the ...