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Interareal differences exhibit a temporal hourglass pattern, dividing human neocortical development into three major phases. During the first phase, in the first six months after conception, general architecture of brain regions is largely formed by a burst of genetic activity, which is distinct for specific regions of the neocortex.
The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into the closed neural tube. In humans, neural tube closure usually occurs by the fourth week of pregnancy (the 28th day after conception). Stages of neural tube formation.
These brain vesicles further divide into subregions. The prosencephalon gives rise to the telencephalon and diencephalon, and the rhombencephalon generates the metencephalon and myelencephalon. The hindbrain, which is the evolutionarily most ancient part of the chordate brain, also divides into different segments called rhombomeres.
The resulting zygote then gives rise to an embryo, which will grow into a new diploid individual, known as a sporophyte. In seed plants, a structure called the ovule contains the female gametophyte. The gametophyte produces an egg cell. After fertilization, the ovule develops into a seed containing the embryo. [14]
Human embryology is the study of this development during the first eight weeks after fertilization. The normal period of gestation (pregnancy) is about nine months or 36 weeks. The germinal stage refers to the time from fertilization through the development of the early embryo until implantation is completed in the uterus .
It is hypothesized in [66] that the growing structure copies the axonal development of the human brain: the earliest developing connections (axonal fibers) are common at most of the subjects, and the subsequently developing connections have larger and larger variance, because their variances are accumulated in the process of axonal development.
Development before birth, or prenatal development (from Latin natalis 'relating to birth') is the process in which a zygote, and later an embryo, and then a fetus develops during gestation. Prenatal development starts with fertilization and the formation of the zygote , the first stage in embryonic development which continues in fetal ...
In human pregnancy, prenatal development is also called antenatal development. The development of the human embryo follows fertilization , and continues as fetal development . By the end of the tenth week of gestational age , the embryo has acquired its basic form and is referred to as a fetus .