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Stages of development of the brain vesicles. Four neural tube subdivisions each eventually develop into distinct regions of the central nervous system by the division of neuroepithelial cells: the forebrain (prosencephalon), the midbrain (mesencephalon), the hindbrain (rhombencephalon) and the spinal cord.
Interareal differences exhibit a temporal hourglass pattern, dividing human neocortical development into three major phases. During the first phase, in the first six months after conception, general architecture of brain regions is largely formed by a burst of genetic activity, which is distinct for specific regions of the neocortex.
These brain vesicles further divide into subregions. The prosencephalon gives rise to the telencephalon and diencephalon, and the rhombencephalon generates the metencephalon and myelencephalon. The hindbrain, which is the evolutionarily most ancient part of the chordate brain, also divides into different segments called rhombomeres.
Stages of neuronal development in the fetal cerebral cortex Model of mammalian neurogenesis [4]. During embryonic development, the mammalian central nervous system (CNS; brain and spinal cord) is derived from the neural tube, which contains NSCs that will later generate neurons. [3]
The resulting zygote then gives rise to an embryo, which will grow into a new diploid individual, known as a sporophyte. In seed plants, a structure called the ovule contains the female gametophyte. The gametophyte produces an egg cell. After fertilization, the ovule develops into a seed containing the embryo. [14]
The development of the neural tube will give rise to the brain and spinal cord. [1] Vertebrates develop a neural crest that differentiates into many structures, including bones, muscles, and components of the central nervous system. Differentiation of the ectoderm into the neural crest, neural tube, and surface ectoderm is sometimes referred to ...
During embryonic development, neural crest cells from each neuromere prompt the development of the nerves and arteries, helping to support the development of craniofacial tissues. If gene expression goes wrong, it can have severe effects on the developing embryo, causing abnormalities like craniofacial clefts, also known as cleft palates . [ 1 ]
It is hypothesized in [66] that the growing structure copies the axonal development of the human brain: the earliest developing connections (axonal fibers) are common at most of the subjects, and the subsequently developing connections have larger and larger variance, because their variances are accumulated in the process of axonal development.