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Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [1] [7] [2] One nanogram per millilitre (1 ng/mL) is equivalent to 2.5 nanomoles per litre (2.5 nmol/L). Severe deficiency: < 12 ng/mL = < 30 nmol/L [2]
Serum 25(OH)D concentration is used as a biomarker for vitamin D deficiency. Units of measurement are either ng/mL or nmol/L, with one ng/mL equal to 2.5 nmol/L. There is not a consensus on defining vitamin D deficiency, insufficiency, sufficiency, or optimal for all aspects of health. [19]
Vitamin D toxicity, or hypervitaminosis D, is the toxic state of an excess of vitamin D.The normal range for blood concentration of 25-hydroxyvitamin D in adults is 20 to 50 nanograms per milliliter (ng/mL).
Serum concentrations above 50 ng/mL may be cause for concern. Common, most foods do not contain vitamin D, indicating that a deficiency will occur unless people get sunlight exposure or eat manufactured foods purposely fortified with vitamin D. Vitamin D deficiency is a known cause of rickets, and has been linked to numerous other health ...
A broad reference range of 20 to 150 nmol/L (8-60 ng/mL) has also been suggested, [16] while other studies have defined levels below 80 nmol/L (32 ng/mL) as indicative of vitamin D deficiency. [ 17 ] Increasing calcifediol levels up to levels of 80 nmol/L (32 ng/mL) are associated with increasing the fraction of calcium that is absorbed from ...
ng/mL or μg/L 6.8 [128] 36 [128] 11 [128] nmol/L Vitamin B 9 (Folic acid/Folate) – Red blood cells: 200 [126] 600 [126] ng/mL or μg/L 450 [128] 1400 [128] nmol/L Pregnant: 400 [126] ng/mL or μg/L 900 [126] nmol/L Vitamin B 12 (Cobalamin) 130, [129] 160 [130] 700, [129] 950 [130] ng/L 100, [131] 120 [5] 520, [131] 700 [5] pmol/L Homocysteine
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Vitamin D (the inactive version) is mainly from two forms: vitamin D 3 and vitamin D 2. Vitamin D 3, or cholecalciferol, is formed in the skin after exposure to sunlight or ultra violet radiation or from D 3 supplements or fortified food sources. Vitamin D 2, or ergocalciferol, is obtained from D 2 supplements or fortified food sources. [3]