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  2. Plasmid-mediated resistance - Wikipedia

    en.wikipedia.org/wiki/Plasmid-mediated_resistance

    Since many R-factors contain F-plasmids, antibiotic resistance can be easily spread among a population of bacteria. [19] Also, R-factors can be taken up by "DNA pumps" in their membranes via transformation , [ 20 ] or less commonly through viral mediated transduction , [ 21 ] or via bacteriophage, although conjugation is the most common means ...

  3. Virulence factor - Wikipedia

    en.wikipedia.org/wiki/Virulence_factor

    Small molecules being investigated for their ability to inhibit virulence factors and virulence factor expression include alkaloids, [9] flavonoids, [10] and peptides. [11] Experimental studies are done to characterize specific bacterial pathogens and to identify their specific virulence factors.

  4. Enterococcus faecalis - Wikipedia

    en.wikipedia.org/wiki/Enterococcus_faecalis

    [7] [8] Several virulence factors are thought to contribute to E. faecalis infections. A plasmid -encoded hemolysin , called the cytolysin , is important for pathogenesis in animal models of infection, and the cytolysin in combination with high-level gentamicin resistance is associated with a five-fold increase in risk of death in human ...

  5. Multidrug-resistant bacteria - Wikipedia

    en.wikipedia.org/wiki/Multidrug-resistant_bacteria

    A variety of different bacteria - testing for antimicrobial resistance. Multidrug-resistant bacteria (MDR bacteria) are bacteria that are resistant to three or more classes of antimicrobial drugs. [1] MDR bacteria have seen an increase in prevalence in recent years [clarification needed] [2] and pose serious risks to public health.

  6. Drug resistance - Wikipedia

    en.wikipedia.org/wiki/Drug_resistance

    An illustrative diagram explaining drug resistance. Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. [1] The term is used in the context of resistance that pathogens or cancers have "acquired", that is, resistance has evolved.

  7. Multiple drug resistance - Wikipedia

    en.wikipedia.org/wiki/Multiple_drug_resistance

    Multiple drug resistance (MDR), multidrug resistance or multiresistance is antimicrobial resistance shown by a species of microorganism to at least one antimicrobial drug in three or more antimicrobial categories. [1] Antimicrobial categories are classifications of antimicrobial agents based on their mode of action and specific to target ...

  8. Limiting factor - Wikipedia

    en.wikipedia.org/wiki/Limiting_factor

    The identification of a factor as limiting is possible only in distinction to one or more other factors that are non-limiting. Disciplines differ in their use of the term as to whether they allow the simultaneous existence of more than one limiting factor (which may then be called "co-limiting"), but they all require the existence of at least one non-limiting factor when the terms are used.

  9. c-Met inhibitor - Wikipedia

    en.wikipedia.org/wiki/C-Met_inhibitor

    [10] [13] All these factors affect the survival of cells, their proliferation and motility. They also lead to cancers and resistance to therapies which aim to treat them. [13] Patients with aberrant c-Met activity usually have a poor prognosis, aggressive disease, increased metastasis and shortened survival. [10]