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Hydroxyapatite (IMA name: hydroxylapatite [5]) (Hap, HAp, or HA) is a naturally occurring mineral form of calcium apatite with the formula Ca 5 (PO 4) 3 (OH), often written Ca 10 (PO 4) 6 (OH) 2 to denote that the crystal unit cell comprises two entities. [6] It is the hydroxyl endmember of the complex apatite group.
The human body is composed of approximately: 64% water, 20% protein, 10% fat, 1% carbohydrate, 5% minerals. [1] The decomposition of soft tissue is characterized by the breakdown of these macromolecules, and thus a large proportion of the decomposition products should reflect the amount of protein and fat content initially present in the body. [4]
P11-4 is a self-assembling β-peptide. It builds a 3-D bio-matrix with binding sites for Calcium-ions serving as nucleation point for hydroxyapatite (tooth mineral) formation. The high affinity to tooth mineral is based on matching distances of Ca-ion binding sites on P11-4 and Ca spacing in the crystal lattice of hydroxyapatite.
Calcium hydroxyphosphate (calcium phosphate tribasic, tribasic calcium phosphate, hydroxyapatite, HAp) is an inorganic chemical compound that is made up of calcium, hydrogen, oxygen and phosphorus. Its formula is Ca 5 (OH)(PO 4) 3. [1] It is found in the body and as the mineral hydroxyapatite. [citation needed]
The most common biogenic phosphate is hydroxyapatite (HA), a calcium phosphate (Ca 10 (PO 4) 6 (OH) 2) and a naturally occurring form of apatite. It is a primary constituent of bone, teeth, and fish scales. [33] Bone is made primarily of HA crystals interspersed in a collagen matrix—65 to 70% of the mass of bone is HA.
Hydroxyapatite, also known as hydroxylapatite, is the major component of tooth enamel and bone mineral. A relatively rare form of apatite in which most of the OH groups are absent and containing many carbonate and acid phosphate substitutions is a large component of bone material.
The plasma membrane Ca 2+ ATPase (PMCA) is a transport protein in the plasma membrane of cells that functions as a calcium pump to remove calcium (Ca 2+) from the cell. PMCA function is vital for regulating the amount of Ca 2+ within all eukaryotic cells.
Tricalcium phosphate is produced commercially by treating hydroxyapatite with phosphoric acid and slaked lime. [4]It cannot be precipitated directly from aqueous solution. Typically double decomposition reactions are employed, involving a soluble phosphate and calcium salts, e.g. (NH 4) 2 HPO 4 + Ca(NO 3
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