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Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.
However, the neurotoxic side effects occurring at the required dosages have prevented the widespread use of metronidazole as an adjuvant agent in radiation therapy. [33] However, other nitroimidazoles derived from metronidazole such as nimorazole with reduced electron affinity showed less serious neuronal side effects and have found their way ...
However, researchers recently carried out a study looking at the effects of an age-reversal pill on dogs, and – while it might sound like something from a sci-fi movie – their findings give us ...
Side effects in dogs and cats include hypersalivation, diarrhea, loss of appetite, and vomiting. [12] [16] Eight percent of dogs taking maropitant at doses meant to prevent motion sickness vomited right after, likely due to the local effects maropitant had on the gastrointestinal tract. Small amounts of food beforehand can prevent such post ...
Reverse tolerance or drug sensitization is a pharmacological phenomenon describing subjects' increased reaction (positive or negative) to a drug following its repeated use. [4] Not all drugs are subject to reverse tolerance. This is the opposite of drug tolerance, in which the effect or the subject's reaction decreases following its repeated ...
There is no indication that a dog with this type of cancer could avoid surgery. If the tumor is small and can be removed completely, the dog will have a much better prognosis. If surgery is not an ...
In dogs, sheep, horses, and cattle, the half-life is very short: only 1.21– 5.97 minutes. Complete elimination of the drug can take up to 23 minutes in sheep and up to 49 minutes in horses. [1] [3] In young rats the half-life is one hour. [18] Xylazine has a large volume of distribution of V d = 1.9 – 2.5 for horses, cattle, sheep, and dogs ...
Patient's appearance of the jaundice side effect. Clarithromycin may cause gastrointestinal adverse effects including vomiting, nausea, taste alteration and abdominal pain. [39] This medication can also cause liver toxicity. [39] Symptoms of liver damage include anorexia, dark urine, jaundice, tender abdomen and pruritus. [39]