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The ingestion of neem oil is potentially toxic and can cause metabolic acidosis, seizures, kidney failure, encephalopathy and severe brain ischemia in infants and young children. [2] [8] [9] Neem oil should not be consumed alone without any other solutions, particularly by pregnant women, women trying to conceive or children. [2]
Azadirachta indica, commonly known as neem, margosa, nimtree or Indian lilac, [3] is a tree in the mahogany family Meliaceae. It is one of the two species in the genus Azadirachta . It is native to the Indian subcontinent and to parts of Southeast Asia , but is naturalized and grown around the world in tropical and subtropical areas.
Although toxic, was used historically in Italy by women to enlarge their pupils, as well as a sedative, among other uses. The name itself means "beautiful woman" in Italian. [27]. Azadirachta indica: Neem: Used in India to treat worms, malaria, rheumatism and skin infections among many other things. Its many uses have led to neem being called ...
Melia dubia Commonly known as Malabar Neem, Maha Neem, Gora Neem, or Barma Dhek. This is one of the most important industrial tree species that has rapidly expanded in the Indian subcontinents in recent decades.
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This molecule can also be found in neem oil at 0.12%. [3] Among the metabolites present in neem, nimbin is the least present chemical compound. [15] Nimbin biosynthesis is not influenced by environmental conditions [17] (temperature, rainfall, humidity…) because neem trees from the same agro-climatic zone can have very different nimbin ...
Azadirachtin, a chemical compound belonging to the limonoid group, is a secondary metabolite present in neem seeds. It is a highly oxidized tetranortriterpenoid which boasts a plethora of oxygen-bearing functional groups, including an enol ether , acetal, hemiacetal , tetra-substituted epoxide and a variety of carboxylic esters .
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