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Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1]
In addition, other specific markers of macrophage activation (e.g. soluble CD163), and lymphocyte activation (e.g. soluble IL-2 receptor) can be helpful. NK cell function analysis may show depressed NK function, or, flow cytometry may show a depressed NK cell population. [4]
Fever is a common symptom in patients with sJIA, characterized by sudden temperature rise above 39 °C and then a sudden drop. Over 80% of patients have a salmon-colored macular or maculopapular rash, which can be migratory and nonpruritic. Arthritis can develop weeks, months, or even years after onset and can affect various joints.
Psoriasis affects 2–3% of the Caucasian population, and psoriatic arthritis affects up to 30% of those. [7] Arthritis mutilans presents in about 5–16% of psoriatic arthritis cases, involves osteolysis of the DIP and PIP joints, and can include bone edema, bone erosions, and new bone growth. [8]
The most commonly involved joints are the two near the ends of the fingers and the joint at the base of the thumbs, the knee and hip joints, and the joints of the neck and lower back. [1] The symptoms can interfere with work and normal daily activities. [1] Unlike some other types of arthritis, only the joints, not internal organs, are affected ...
One study also examined habitual knuckle cracking’s affect on grip strength, and found it to be null. Osteoarthritis is characterized by the deterioration of cartilage around the joint, which ...
Arthritis is a general medical term used to describe a disorder that affects joints. [2] Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. [2] [3] In certain types of arthritis, other organs such as the skin are also affected. [5]
By DR. KAREN LATIMER My ten-year-old has this very annoying habit of cracking her joints – all of them – knuckles, back, wrists, ankles. If it can bend, she can crack it. The sound itself ...