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  2. Polygenic score - Wikipedia

    en.wikipedia.org/wiki/Polygenic_score

    In genetics, a polygenic score (PGS) is a number that summarizes the estimated effect of many genetic variants on an individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk score (PRS or PR score [1]) or genetic risk score. The score reflects an ...

  3. Polygene - Wikipedia

    en.wikipedia.org/wiki/Polygene

    A polygene is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance [1]), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of Mendelian inheritance.

  4. Complex traits - Wikipedia

    en.wikipedia.org/wiki/Complex_traits

    It is a complex trait because multiple genetic and environmental factors impact the phenotype. [13] [14] The phenotype before the threshold is referred to as normal or absent, and after the threshold as lethal or present. These traits are often examined in a medical context, because many diseases exhibit this pattern or similar. [9]

  5. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    Four different traits can be identified by pedigree chart analysis: autosomal dominant, autosomal recessive, x-linked, or y-linked. Partial penetrance can be shown and calculated from pedigrees. Penetrance is the percentage expressed frequency with which individuals of a given genotype manifest at least some degree of a specific mutant ...

  6. Mendelian traits in humans - Wikipedia

    en.wikipedia.org/wiki/Mendelian_traits_in_humans

    Autosomal dominant A 50/50 chance of inheritance. Sickle-cell disease is inherited in the autosomal recessive pattern. When both parents have sickle-cell trait (carrier), a child has a 25% chance of sickle-cell disease (red icon), 25% do not carry any sickle-cell alleles (blue icon), and 50% have the heterozygous (carrier) condition. [1]

  7. Oligogenic inheritance - Wikipedia

    en.wikipedia.org/wiki/Oligogenic_inheritance

    Oligogenic inheritance (Greek ὀλίγος – ὀligos = few, a little) describes a trait that is influenced by a few genes. Oligogenic inheritance represents an intermediate between monogenic inheritance in which a trait is determined by a single causative gene, and polygenic inheritance, in which a trait is influenced by many genes and often environmental factors.

  8. Pedigree chart - Wikipedia

    en.wikipedia.org/wiki/Pedigree_chart

    A pedigree chart is a diagram that shows the occurrence of certain traits through different generations of a family, [1] [2] most commonly for humans, show dogs, and race horses. [ citation needed ] Definition

  9. File:Pedigree-chart-example.svg - Wikipedia

    en.wikipedia.org/wiki/File:Pedigree-chart...

    The following other wikis use this file: Usage on ar.wikipedia.org علم الوراثة; Usage on bn.wikipedia.org বংশাণুবিজ্ঞান