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Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. [1] It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. [1]
Bacterial vaginosis (BV) is an infection of the vagina caused by excessive growth of bacteria. [ 6 ] [ 12 ] Common symptoms include increased vaginal discharge that often smells like fish. [ 2 ] The discharge is usually white or gray in color. [ 2 ]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
Bacterial vaginosis is caused by an imbalance of the naturally occurring bacteria in the vagina. [ 1 ] [ 2 ] The normally predominant species of Lactobacilli are markedly reduced. [ 3 ] This is the list of organisms that are found in the vagina that are associated with bacterial vaginosis , an infectious disease of the vagina caused by ...
Lactobacillus jensenii is a lactic acid bacteria species in the genus Lactobacillus.. It is one of the four main species of Lactobacillus considered to be the major part of the vaginal flora, along with Lactobacillus crispatus, Lactobacillus gasseri, and Lactobacillus iners.
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Bacterial vaginosis results in altered populations and ratios of the normal microbiota. [ 10 ] [ 3 ] [ 11 ] There has been no link demonstrated between taking oral probiotics and maintaining normal microbiota populations of lactobacilli.
A single study suggests superiority of azithromycin over doxycycline. [34] Another alternative is to use a parenteral regimen with ceftriaxone or cefoxitin plus doxycycline. [ 27 ] Clinical experience guides decisions regarding transition from parenteral to oral therapy, which usually can be initiated within 24–48 hours of clinical improvement.
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