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Apical dendrites are the most distal along the ascending trunk, and reside in layer 1. These distal apical dendrites receive synaptic input from related cortical as well as globally modulatory subcortical projections. Basal dendrites include shorter radially distributed dendrites which receive input from local pyramidal cells and interneurons. [4]
A basal dendrite is a dendrite that emerges from the base of a pyramidal cell [1] that receives information from nearby neurons and passes it to the soma, or cell body. Due to their direct attachment to the cell body itself, basal dendrites are able to deliver strong depolarizing currents and therefore have a strong effect on action potential output in neurons. [2]
A reconstruction of a pyramidal cell. Soma and dendrites are labeled in red, axon arbor in blue. (1) Soma, (2) Basal dendrite, (3) Apical dendrite, (4) Axon, (5) Collateral axon. One of the main structural features of the pyramidal neuron is the conic shaped soma, or cell body, after which the neuron is named.
A dendrite (from Greek δένδρον déndron, "tree") or dendron is a branched cytoplasmic process that extends from a nerve cell that propagates the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.
T-type and R-type voltage-gated calcium channels have been found in basal dendrites, and it is thought that the activation of these channels during action potential bursts leads to the generation of dendritic calcium spikes. [10] T-type and R-type channels are all part of the alpha 1 subunit class of calcium channels.
Corneal abrasions are a common eye problem in which the eye's cornea (an important part of the eye that allows light to enter properly) is scratched. In order to treat it, a doctor has to ...
After this transition, radial glia retain many of the original characteristics of neuroepithelial cells including: their apical-basal polarity, their position along the lateral ventricles of the developing cortex, and the phasic migration of their nuclei depending on their location with the cell cycle (termed “interkinetic nuclear migration”).
The medial perforant path synapses onto the proximal dendritic area of the granule cells, whereas the lateral perforant path does so onto their distal dendrites. Most lateral views of the dentate gyrus may appear to suggest a structure consisting of just one entity, but medial movement may provide evidence of the ventral and dorsal parts of the ...