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Another autoimmune skin disease which can occur in dogs is vitiligo. In addition to humans, vitiligo can be found in a variety of animals, including cats, horses, and dogs. Vitiligo is a type of autoimmune disease that damages melanocytes in the skin, lips, and oral cavity. Melanocytes are cells that contain pigments such as melanin.
Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is taken orally or intravenously for rheumatoid arthritis , psoriasis , Crohn's disease , nephrotic syndrome , eczema , and in organ transplants to prevent rejection .
Other autoimmune diseases include bullous pemphigoid and epidermolysis bullosa acquisita. Treatment of autoimmune skin diseases in dogs requires methods to reduce the abnormal immune response; steroids, azathioprine and other drugs are used as immunosuppressive agents. [1]
Sebaceous adenitis and hair loss in a dog. Sebaceous adenitis is an uncommon skin disease found in some breeds of dog, and more rarely in cats, rabbits and horses. [1] characterised by an inflammatory response against the dog's sebaceous glands (glands found in the hair follicles in the skin dermis), which can lead to the destruction of the gland.
Chronic superficial keratitis (CSK), also known as pannus or Uberreiter's disease, is an inflammatory condition of the cornea in dogs, particularly seen in the German Shepherd. Both eyes are usually affected. The corneas gradually become pigmented and infiltrated by blood vessels, and the dog may eventually become blind.
Discoid lupus erythematosus (DLE) is an uncommon autoimmune disease of the basal cell layer of the skin. It occurs in humans [1] and cats, more frequently occurring in dogs. It was first described in dogs by Griffin and colleagues in 1979. [2] [3] DLE is one form of cutaneous lupus erythematosus (CLE). DLE occurs in dogs in two forms: a ...
It is a rare disease in dogs, with cats seven to ten times more likely to be infected. The disease in dogs can affect the lungs and skin, but more commonly the eye and central nervous system. [20] Ringworm is a fungal skin disease that in dogs is caused by Microsporum canis (70%), Microsporum gypseum (20%), and Trichophyton mentagrophytes (10% ...
Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
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