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Substances that may cause this toxidrome include cocaine, amphetamine and compounds based upon amphetamine's structure such as ephedrine , methamphetamine, phenylpropanolamine and pseudoephedrine. The bronchodilator salbutamol may also cause this toxidrome. It may appear very similar to the anticholinergic toxidrome, but is distinguished by ...
An overdose of gabapentinoids usually consists of severe drowsiness, severe ataxia, blurred vision, slurred speech, severe uncontrollable jerking motions, and anxiety. [ 59 ] [ 60 ] Like most anticonvulsants, pregabalin and gabapentin have an increased risk of suicidal thoughts and behaviors .
Side effects are typical of hypnotic benzodiazepines, though temazepam has more pronounced CNS depressant effects, and include somnolence, sedation, dizziness, fatigue, ataxia, headache, lethargy, impairment of memory and learning, longer reaction time and impairment of motor functions (including coordination problems), [26] slurred speech ...
Around 70% of patients with narcolepsy also experience cataplexy episodes, according to U.S. government data, which can cause slurred speech or muscle weakness triggered by intense emotions.
It can cause a visible slowing of physical and emotional reactions, including speech and affect. [1] Psychomotor retardation is most commonly seen in people with major depression and in the depressed phase of bipolar disorder; [2] it is also associated with the adverse effects of certain drugs, such as benzodiazepines. [3]
Infusions of the drug gave her headaches so severe they sent her to bed. A week after the third dose, she was at a restaurant with her best friend when her speech slurred and she had a seizure ...
Common clinical features of ataxic dysarthria include abnormalities in speech modulation, rate of speech, explosive or scanning speech, slurred speech, irregular stress patterns, and vocalic and consonantal misarticulations. [13] [14] Ataxic dysarthria is associated with damage to the left cerebellar hemisphere in right-handed patients. [15]
An overdose of pregabalin usually consists of severe drowsiness, severe ataxia, blurred vision, slurred speech, uncontrollable jerking motions , and anxiety. [92] In one case study, macular detachment was reported with overdose [ 93 ] Despite these symptoms an overdose is not usually fatal unless mixed with another CNS depressant .