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William Bradley Coley (January 12, 1862 – April 16, 1936) was an American bone surgeon and cancer researcher best known for his early contributions to the study of cancer immunotherapy, specifically causing infection as a way to fight cancer, a practice used as far back as 1550 BC. [1]
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Coley's toxins (also called Coley's toxin, [1] Coley's vaccine, [2] Coley vaccine, Coley's fluid or mixed bacterial vaccine) is a mixture containing toxins filtered from killed bacteria of species Streptococcus pyogenes and Serratia marcescens, named after William Coley, a surgical oncologist at the Hospital for Special Surgery who developed the mixture in the late 19th century as a treatment ...
1893 – Use of live bacteria and bacterial lysates to treat tumors – "Coley's Toxins", based on Busch and Fehleisen experiences (William B. Coley) 1894 – Bacteriolysis (Richard Pfeiffer) 1896 – An antibacterial, heat-labile serum component is described (Jules Bordet) 1900 – Antibody formation theory (Paul Ehrlich)
Engineers during World War Two test a model of a Halifax bomber in a wind tunnel, an invention that dates back to 1871.. The following is a list and timeline of innovations as well as inventions and discoveries that involved British people or the United Kingdom including the predecessor states before the Treaty of Union in 1707, the Kingdom of England and the Kingdom of Scotland.
He is buried in the porch of the church of East Ardsley, Yorkshire and a memorial plaque which reads: "Beneath this porch lies buried John Field 1520-1587 He was the first astronomer in this country to make known the discoveries of Copernicus." [1] His library passed into the hands of William Coley of York, who afterwards returned it to the family.
With the exception of William Coley who in the late 19th century felt that the rate of cure after surgery had been higher before asepsis (and who injected bacteria into tumours with mixed results), cancer treatment became dependent on the individual art of the surgeon at removing a tumour. The underlying cause of his results might be that ...
CRI was created in honor of Nauts' father, William Coley (1862–1936), an American orthopedic surgeon and a pioneer of cancer immunotherapy. Grounded in Dr. Coley’s pioneering work, the Cancer Research Institute focuses on immunological treatments for cancer, both as a single treatment approach as well as a complement and enhancer to ...