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Aspergillus penicillioides is a species of fungus in the genus Aspergillus, and is among the most xerophilic fungi. [1]Aspergillus penicillioides is typically found in indoor air, house dust, and on substrates with low water activity, such as dried food, papers affected by foxing, and inorganic objects such as binocular lenses. [2]
Health problems associated with high levels of airborne mold spores include allergic reactions, asthma episodes, irritations of the eye, nose and throat, sinus congestion, and other respiratory problems. [22] Several studies and reviews have suggested that childhood exposure to dampness and mold might contribute to the development of asthma.
In hematologic patients with invasive aspergillosis, the galactomannan test can make the diagnosis in a noninvasive way. Galactomannan is a component of the fungal wall. [ 13 ] False-positive Aspergillus galactomannan tests have been found in patients on intravenous treatment with some antibiotics or fluids containing gluconate or citric acid ...
Allergic bronchopulmonary aspergillosis; Other names: ABPA, Hinson-Pepys disease. The chest radiograph of an allergic bronchopulmonary aspergillosis patient shown with left-sided perihilar opacity (blue arrow) along with non-homogeneous infiltrates (transient pulmonary infiltrates indicated by red arrows) in all zones of both lung fields.
Infections by other fungi, including Saccharomyces, Aspergillus (as in aspergillemia, also called invasive aspergillosiis) and Cryptococcus, are also called fungemia. It is most commonly seen in immunosuppressed or immunocompromised patients with severe neutropenia, cancer patients, or in patients with intravenous catheters.
Aspergillus species are highly aerobic and are found in almost all oxygen-rich environments, where they commonly grow as molds on the surface of a substrate, as a result of the high oxygen tension. Commonly, fungi grow on carbon-rich substrates like monosaccharides (such as glucose ) and polysaccharides (such as amylose ).
Gliotoxin is hypothesized to be an important virulence factor in Aspergillus fumigatus. [17] Experiments have demonstrated that gliotoxin is isolated in the highest concentrations from Aspergillus fumigatus in comparison to other Aspergillus species. This species of fungi is the most common cause of aspergillosis in humans.
In a study, to test the toxicity of OTA in rats, a different dietary dose of OTA was administered to male Fischer rats. [33] Only chronic administration of OTA manifested as renal carcinogenesis in these rats. [33] Low levels of Aspergillus ochraceus contamination caused mycotoxic nephropathy in farm pigs and chickens from Bulgaria. [10]