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Example of a traditional set-up for the tail flick assay. The tail flick assay or tail flick test uses a high-intensity beam of light aimed at a rodent's tail to detect nociception. [1] In normal rodents, the noxious heat sensation induced by the beam of light causes a prototypical movement of the tail via the flexor withdrawal reflex. [2]
[1] The main strength of the tail suspension test is its predictive validity– performance on the test can be altered by drugs that improve depressive symptoms in people. Specifically, if antidepressant agents are administered before the test, the animal will struggle for a longer period of time than if not and exhibit more escape behaviors. [1]
Tail flick test apparatus. The tail flick test is a test of the pain response in animals, similar to the hot plate test. It is used in basic pain research and to measure the effectiveness of analgesics, by observing the reaction to heat. It was first described by D'Amour and Smith in 1941. [1]
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A mortgage point could cost 1% of your mortgage amount, which means about $5,000 on a $500,000 home loan, with each point lowering your interest rate by about 0.25%, depending on your lender and loan.
0.17 minutes 10 2: hectosecond: 100: 1.67 minutes (or 1 minute 40 seconds) 10 3: kilosecond: 1 000: 16.7 minutes (or 16 minutes and 40 seconds) 10 6: megasecond: 1 000 000: 11.6 days (or 11 days, 13 hours, 46 minutes and 40 seconds) 10 9: gigasecond: 1 000 000 000: 31.7 years (or 31 years, 252 days, 1 hour, 46 minutes, 40 seconds, assuming that ...
Aim for 150 minutes a week of moderate-intensity aerobic exercise — up to 30 minutes a day, five days a week — and three sets of muscle-strengthening exercises twice a week. We know this is a lot.
The tattooed corpse of a woman was found bizarrely stuffed in a refrigerator dumped in some New Jersey woods — and cops say they need the public’s help identifying her.