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There are four paired deep cerebellar nuclei embedded in the white matter centre of the cerebellum. The nuclei are the fastigial, globose, emboliform, and dentate nuclei. In lower mammals the emboliform nucleus appears to be continuous with the globose nucleus, and these are known together as the interposed nucleus. [1]
The emboliform nucleus is a deep cerebellar nucleus that lies immediately to the medial side of the dentate nucleus, partly covering its hilum. It is one of the four pairs of deep cerebellar nuclei, which are from lateral to medial: the dentate, emboliform, globose and fastigial. These nuclei can be seen using Weigert's elastic stain.
The eight cerebellar nuclei, located within the deep white matter of each cerebellar hemisphere, are grouped into pairs, with one of each pair in each of the two hemispheres. As a chunk of tissue, the dentate nucleus with overlying cerebellar cortex makes up a functional unit called the cerebrocerebellum. Thus, there is a part of cerebellum ...
The fastigial nucleus (roof nucleus-1) is located in each cerebellar hemisphere. It is one of the four paired deep cerebellar nuclei of the cerebellum . It is made up of two sections: the rostral fastigial nucleus and the caudal fastigial nucleus.
The function of the cerebellar cortex is essentially to modulate information flowing through the deep nuclei. The microcircuitry of the cerebellum is schematized in Figure 5. Mossy and climbing fibers carry sensorimotor information into the deep nuclei, which in turn pass it on to various premotor areas, thus regulating the gain and timing of ...
The interposed nucleus is the combined paired globose and emboliform nuclei, (deep cerebellar nuclei) on either side of the cerebellum. [1] [2] It is located in the roof of the fourth ventricle, lateral to the fastigial nucleus. The emboliform nucleus is the anterior interposed nucleus, and the globose nucleus is the posterior interposed ...
These axons ascend to the pons where they join the superior cerebellar peduncle to enter the cerebellum. Once in the deep white matter of the cerebellum, the axons recross the midline, give off collaterals to the globose and emboliform nuclei, and terminate in the cortex of the anterior lobe and vermis of the posterior lobe.
The inferior olivary nucleus (ION) is a structure found in the medulla oblongata underneath the superior olivary nucleus. [1] In vertebrates, the ION is known to coordinate signals from the spinal cord to the cerebellum to regulate motor coordination and learning. [ 2 ]