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NOBS is the main bleach activator used in the U.S.A. and Japan. [4] Compared to TAED, which is the predominant bleach activator used in Europe, NOBS is efficient at much lower temperatures. At 20 °C NOBS is 100 times more soluble than TAED in water. [5]
The N-terminal acts as an allosteric regulator of C-terminal; the C-terminal is the only one involved in the catalytic activity. HK-I is regulated by the concentration of G6P, where G6P acts as a feedback inhibitor. At low G6P concentration, HK-I is activated; at high G6P concentration, the HK-I is inhibited. [1]
[3] [1] [4] [5] NV-5138 works by binding to and modulating sestrin2, a cellular sensor protein for the amino acid leucine, which is a natural activator of mammalian target of rapamycin complex 1 (mTORC1) signaling pathway.
Activator may refer to: Activator (genetics) , a DNA-binding protein that regulates one or more genes by increasing the rate of transcription Activator (phosphor) , a type of dopant used in phosphors and scintillators
Tetraacetylethylenediamine, commonly abbreviated as TAED, is an organic compound with the formula (CH 3 C(O)) 2 NCH 2 CH 2 N(C(O)CH 3) 2. It is a white solid commonly used as a bleach activator in laundry detergents and in the production of paper pulp. TAED is synthesized through the acetylation of ethylenediamine.
By inhibiting PAI-1, it increases activity of the enzymes tissue plasminogen activator and urokinase, which are involved in the blood clotting cascade. It has been researched for conditions such as hepatic steatosis and diabetic nephropathy, and while it has not been developed for medical use, it is widely used in scientific research. [1] [2 ...
CPSI is regulated by N-acetylglutamate which acts as an obligate allosteric activator of CPS1. NAG, by binding to domain L4, triggers changes in the A-loop and in Arg1453 that result in changing interactions with the T′-loop of domain L3, which reorganizes completely from a β-hairpin in the apo form to a widened loop in the ligand-bound form.
In phosphors and scintillators, the activator is the element added as dopant to the crystal of the material to create desired type of nonhomogeneities. In luminescence , only a small fraction of atoms, called emission centers or luminescence centers , emit light.