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For acute pericarditis to formally be diagnosed, two or more of the following criteria must be present: chest pain consistent with a diagnosis of acute pericarditis (sharp chest pain worsened by breathing in or a cough), a pericardial friction rub, a pericardial effusion, and changes on electrocardiogram (ECG) consistent with acute pericarditis ...
The preferred initial diagnostic testing is the ECG, which may demonstrate a 12-lead electrocardiogram with diffuse, non-specific, concave ("saddle-shaped"), ST-segment elevations in all leads except aVR and V1 [11] and PR-segment depression possible in any lead except aVR; [11] sinus tachycardia, and low-voltage QRS complexes can also be seen ...
Constrictive pericarditis is a condition characterized by a thickened, fibrotic pericardium, limiting the heart's ability to function normally. [1] In many cases, the condition continues to be difficult to diagnose and therefore benefits from a good understanding of the underlying cause.
The diagnosis of purulent pericarditis requires a combination of clinical assessment, laboratory tests, and imaging studies. Pericardiocentesis with evaluation of pericardial fluid by culture and microscopy is necessary to make the diagnosis, however several other findings may increase the likelihood of purulent pericarditis.
The Tygerberg score is a clinical decision tool that allows the clinician to decide whether pericarditis is due to tuberculosis or not. It uses five variables: Weight loss (1 point) Night sweats (1 point) Fever (2 points) Serum globulin >40 g/L (3 points) Blood leukocyte count <10 × 10 9 /l (3 points)
Uremic pericarditis is associated with azotemia, and occurs in about 6-10% of kidney failure patients. BUN is normally >60 mg/dL (normal is 7–20 mg/dL). However, the degree of pericarditis does not correlate with the degree of serum BUN or creatinine elevation. The pathogenesis is poorly understood. [2]
Pericarditis can be acute, meaning it happens suddenly or chronic — it can develop over time and may take longer to treat. Both types can disrupt the heart’s normal function, said the American ...
Pericarditis or pleuritis or both Molecular Criterion: NOD2 IVS8+158 or R702W or both, or other rare variants Exclusion Criteria: High titer antinuclear antibodies, inflammatory bowel disease, Blau syndrome, adult sarcoidosis, primary Sjögren syndrome and monogenic autoinflammatory diseases