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Asthma affects approximately 7% of the population of the United States and causes approximately 4,210 deaths per year. [ 13 ] [ 14 ] [ 15 ] In 2005, asthma affected more than 22 million people, including 6 million children, and accounted for nearly 500,000 hospitalizations that same year. [ 16 ]
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.
Acute severe asthma; Airway remodelling; Alcohol-induced respiratory reactions; Allergies in children; Anti-asthmatic agent; Aspirin-exacerbated respiratory disease; Asthma; Asthma and Allergy Friendly; Asthma Life Impact Scale; Asthma phenotyping and endotyping; Asthma trigger; Asthma-COPD overlap; Asthma-related microbes; Asthmagen
The mechanisms behind allergic asthma—i.e., asthma resulting from an immune response to inhaled allergens—are the best understood of the causal factors. In both people with asthma and people who are free of the disease, inhaled allergens that find their way to the inner airways are ingested by a type of cell known as antigen-presenting ...
Sensitizer-induced occupational asthma is an immunologic form of asthma which occurs due to inhalation of specific substances (i.e., high-molecular-weight proteins from plants and animal origins, or low-molecular-weight agents that include chemicals, metals and wood dusts) and occurs after a latency period of several weeks to years. [1]
Brittle asthma is a type of asthma distinguishable from other forms by recurrent, severe attacks. [ 1 ] [ 2 ] [ 3 ] There are two subtypes divided by symptoms: Type 1 and Type 2, [ 4 ] depending on the stability of the patient's maximum speed of expiration, or peak expiratory flow rate (PEFR).
Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
Acute severe asthma, also known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators (inhalers) and corticosteroids. [2] Asthma is caused by multiple genes , some having protective effect, with each gene having its own tendency to be influenced by the environment although a ...