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Individual rats would rarely eat except in the company of other rats. As a result extreme population densities developed in the pen adopted for eating, leaving the others with sparse populations. In the experiments in which the behavioral sink developed, infant mortality ran as high as 96 percent among the most disoriented groups in the population.
Many laboratory animals, including mice and rats, are chronically stressed which can also negatively affect research outcomes and the ability to accurately extrapolate findings to humans. [32] [33] Researchers have also noted that many studies involving mice, rats and other rodents are poorly designed, leading to questionable findings.
Tyron's rat chart. Prior to Robert Tryon’s study of selective rat breeding, concluded in 1942, many psychologists believed that environmental, rather than genetic, differences produced individual behavioral variations. Tryon sought to demonstrate that genetic traits often did, in fact, contribute to behavior.
When used to test venom from venomous creatures, such as snakes, LD 50 results may be misleading due to the physiological differences between mice, rats, and humans. Many venomous snakes are specialized predators on mice, and their venom may be adapted specifically to incapacitate mice; and mongooses may be exceptionally resistant.
Marble burying is an animal model used in scientific research to depict anxiety or obsessive–compulsive disorder (OCD) behavior. It is based on the observation that rats and mice will bury either harmful or harmless objects in their bedding. [1]
Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice , rats have served as an important animal model for research in psychology and biomedical science [ 1 ] , and "lab rat" is ...
Rodent mite dermatitis (also known as rat mite dermatitis) is an often unrecognized ectoparasitosis occurring after human contact with haematophagous mesostigmatid mites that infest rodents, such as house mice, [1] rats [2] and hamsters. [3]
Lymphocytic choriomeningitis (LCM) is a rodent-borne viral infectious disease that presents as aseptic meningitis, encephalitis or meningoencephalitis.Its causative agent is lymphocytic choriomeningitis mammarenavirus (LCMV), a member of the family Arenaviridae.