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Complications: Gastroesophageal reflux disease (GERD), sinusitis, obstructive sleep apnea: ... Asthma is a common long-term inflammatory disease of the airways of the ...
Acute severe asthma, also known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators (inhalers) and corticosteroids. [2] Asthma is caused by multiple genes , some having protective effect, with each gene having its own tendency to be influenced by the environment although a ...
Moreover, another option is the use of cromolyn sodium, which can prevent an asthma attack by halting Ca2+ influx, thus preventing mast cell degranulation and subsequent asthmatic complications [53] Other than drugs, an alternative treatment method is de-sensitization , which involves exposure to a well-controlled, small and increasing amounts ...
Asthma is one of the most common lung diseases in the world, affecting some 262 million people worldwide and causing more than 450,000 deaths annually, per the World Health Organization.While ...
Airway remodelling is a multifaceted process involving multiple airway tissues. These include goblet cell hyperplasia, leading to increased mucus production, and airway smooth muscle hypertrophy (or smooth muscle cell hyperplasia), leading to the release of pro-inflammatory and pro-fibrotic messengers contributing to subepithelial fibrosis.
Estimates of between 0.5 and 3.5% have been made for ABPA burden in asthma, [32] [33] and 1–17.7% in CF. [32] [34] Five national cohorts, detecting ABPA prevalence in asthma (based on GINA estimates), [35] were used in a recent meta-analysis to produce an estimate of the global burden of ABPA complicating asthma. From 193 million people with ...
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