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In probability theory, an experiment or trial (see below) is any procedure that can be infinitely repeated and has a well-defined set of possible outcomes, known as the sample space. [1] An experiment is said to be random if it has more than one possible outcome, and deterministic if it has only one.
Bayesian experimental design provides a general probability-theoretical framework from which other theories on experimental design can be derived. It is based on Bayesian inference to interpret the observations/data acquired during the experiment. This allows accounting for both any prior knowledge on the parameters to be determined as well as ...
In probability theory and statistics, the empirical probability, relative frequency, or experimental probability of an event is the ratio of the number of outcomes in which a specified event occurs to the total number of trials, [1] i.e. by means not of a theoretical sample space but of an actual experiment.
As the number of trials increases, the relative frequencies approach their respective theoretical probabilities, demonstrating the Law of Large Numbers. For example, a fair coin toss is a Bernoulli trial. When a fair coin is flipped once, the theoretical probability that the outcome will be heads is equal to 1 ⁄ 2.
In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups.For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization.
Such optimal probability-measure designs solve a mathematical problem that neglected to specify the cost of observations and experimental runs. Nonetheless, such optimal probability-measure designs can be discretized to furnish approximately optimal designs. [32] In some cases, a finite set of observation-locations suffices to support an ...
Illustration of the power of a statistical test, for a two sided test, through the probability distribution of the test statistic under the null and alternative hypothesis. α is shown as the blue area, the probability of rejection under null, while the red area shows power, 1 − β, the probability of correctly rejecting under the alternative.
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [12] by Abraham Wald in the context of sequential tests of statistical hypotheses. [13]