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Linus Carl Pauling FRS (/ ... Early in 1953 Watson and Crick proposed a correct structure for the DNA double helix. Pauling later cited several reasons to explain how ...
In 1951, Pauling published the structure of the alpha helix, a fundamentally important structural component of proteins. In early 1953, Pauling published a triple helix model of DNA, which subsequently turned out to be incorrect. [3] Both Crick, and particularly Watson, thought that they were racing against Pauling to discover the structure of DNA.
In addition to the variety of verified DNA structures, there have been a range of proposed DNA models that have either been disproven, or lack sufficient evidence.. Some of these structures were proposed during the 1950s before the structure of the double helix was solved, most famously by Linus Pauling.
The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...
Narrated by Jeff Goldblum, it features Watson, Wilkins, Gosling and Peter Pauling (son of Linus Pauling). [27] A play entitled Photograph 51 by Anna Ziegler focuses on the role of X-ray crystallographer Rosalind Franklin in the discovery of the structure of DNA. [28] [29] This play won the third STAGE International Script Competition in 2008. [30]
It covered the discovery of DNA in 1953. [1] Maurice Wilkins and his involvement with the Manhattan Project, speaking in his university office in London; Linus Pauling's son Peter, of Caltech, now lived in Wales; Linus Pauling approached the discovery of the structure of DNA in a much more methodical rigid manner, perhaps in a plodding way, and Pauling was never one to take the same un-thought ...
This photo was given to Watson and Crick by Maurice Wilkins and was critical to their obtaining the correct structure of DNA. Franklin told Crick and Watson that the backbones had to be on the outside. Before then, Linus Pauling, and Watson and Crick, had erroneous models with the chains inside and the bases pointing outwards.
This image, along with the knowledge that Linus Pauling had proposed an incorrect structure of DNA, "mobilised" [9] Watson and Crick to restart model building. With additional information from research reports of Wilkins and Franklin, obtained via Max Perutz, Watson and Crick correctly described the double-helix structure of DNA in 1953.