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Varenicline is indicated for use as an aid to smoking cessation treatment [5] and for the treatment of the signs and symptoms of dry eye disease. [6] Varenicline is used to help people stop smoking tobacco (smoking cessation). A meta-analysis found that 20% of people treated with varenicline remain abstinent from smoking at one year. [15]
In Ontario, Canada, smoking cessation drugs are not covered by provincial drug plans. Thus, a physician can write a prescription for Wellbutrin to assist with giving up the habit of smoking. Sometimes it is also prescribed as second-line treatment of ADHD, often in combination with the stimulant being used, but it was also shown to work on its ...
But experts emphasize that much more research is needed before using the medications off-label for smoking cessation. Popular weight-loss and diabetes medications show promise for curbing smoking ...
However, the investment in NHS stop smoking services is relatively low. A comparison with treatment costs for illicit drug users shows that £585 million is committed for 350,000 problem drug users compared to £56 million for 9 million users of tobacco. This is £6.20 for each smoker, compared to £1,670 per illegal drug user. [22]
Antidepressants: The antidepressant bupropion is considered a first-line medication for smoking cessation and has been shown in many studies to increase long-term success rates. Although bupropion increases the risk of getting adverse events, there is no clear evidence that the drug has more or less adverse effects when compared to a placebo.
It has been found effective in several randomized clinical trials, including in the United States and New Zealand, [1] and is being investigated in additional trials in the United States and a non-inferiority trial in Australia in which it is being compared head-to-head with the smoking cessation aid varenicline (sold in the United States as ...
Bupropion, formerly called amfebutamone, [16] and sold under the brand name Wellbutrin among others, is an atypical antidepressant that is indicated in the treatment of major depressive disorder, seasonal affective disorder and to support smoking cessation.
New strategies are required to solve this significant health issue in the midst of these obstacles in order to promote smoking cessation. Immunotherapy-based methods, such as the use of vaccines to treat addiction, have been documented in the literature since the 1960s and 1970s. [ 23 ]
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