Search results
Results from the WOW.Com Content Network
Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant [1] and in the plasma membrane where it directly activates lipid-gated ion channels. The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2.
The lecithin–sphingomyelin ratio is a marker of fetal lung maturity. The outward flow of pulmonary secretions from the fetal lungs into the amniotic fluid maintains the level of lecithin and sphingomyelin equally until 32–33 weeks gestation, when the lecithin concentration begins to increase significantly while sphingomyelin remains nearly the same.
In enzymology, a phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase (EC 2.7.8.20) is an enzyme that catalyzes the chemical reaction phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose ⇌ {\displaystyle \rightleftharpoons } 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose
Phosphatidylglycerol is a precursor and structural isomer of LBPA. [1] LBPA's stereochemistry is atypical among glycerophospholipids and influences its function within the LE/LY (late endosome/lysosome) system. [1] [2] LBPA makes up 15–20% of all LE/LY phospholipids and is not found in other subcellular membranes. [3]
In enzymology, a CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) is an enzyme that catalyzes the chemical reaction. CDP-diacylglycerol + sn-glycerol 3-phosphate CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate
The enzyme phosphatidylglycerophosphatase (EC 3.1.3.27) catalyzes the following reaction: [1]. phosphatidylglycerophosphate + H 2 O phosphatidylglycerol + phosphate. This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds.
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk .
Cardiolipin (IUPAC name 1,3-bis(sn-3’-phosphatidyl)-sn-glycerol, "sn" designating stereospecific numbering) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.